by Stephen Luther, M.D.
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Optimizing Your Body’s Natural Fuel
What we eat is crucial, but the quality of our food matters more than just counting calories. Fasting has been practiced for centuries, not only for religious reasons but also for its health benefits. It allows us to understand how different foods impact our bodies over time. Intermittent fasting (IF) can be an excellent option for those looking to lose weight or manage conditions such as type 2 diabetes, heart disease, and age-related diseases. By shifting the body’s fuel source from glucose to ketones and fatty acids, fasting improves metabolic health and may even extend life expectancy.
Before making any significant changes to your diet, it’s important to consult with our nutrition team to ensure you’re on the right track.
Chronic Conditions and Their Whole-Body Impact
Metabolic Syndrome (MS) is a condition of insulin resistance characterized by high blood pressure, blood sugar, triglycerides, and low HDL cholesterol, leading to a higher risk of heart disease, stroke, and type 2 diabetes (T2DM). MS and T2DM are also linked to cognitive decline, including memory loss and reduced brain function, increasing the risk of Alzheimer’s disease. These conditions cause inflammation and oxidative stress, further damaging brain cells and reducing cognitive abilities.
The Power of Intermittent Fasting
Increased Lifespan, Mental and Physical Performance
Intermittent fasting can be a powerful lifestyle choice, as it involves eating only during specific periods. This method activates energy-storing organs like the liver and fat tissue, helping to increase lifespan by regulating energy and metabolism. Fasting shifts our fuel source to ketones, which break down fat cells and enhance brain function through increased serotonin and GABA levels.
Brain Health, AMPK Activation and Neurogenesis
Fasting also promotes the growth of new brain cells and improves brain performance, thanks to neurotrophic factors like BDNF. Additionally, it activates AMPK, an enzyme that regulates cellular metabolism and growth, aiding in identifying and combating cellular abnormalities.
Stem Cell Stimulation
Another exciting benefit is the stimulation of stem cells, which are crucial for reducing inflammation and regenerating damaged cells. Fasting can activate stem cells in the bone marrow, immune system, and intestines, doubling the body’s natural resistance to toxins and stress.
Other Health Benefits of Fasting
- Circadian Rhythm: Fasting helps regulate our body’s internal clock, promoting better sleep and preventing insulin resistance, which can lead to chronic diseases.
- Obesity: Fasting has been shown to reduce body weight, with overweight individuals experiencing a 6.5% reduction after a 12-week program. It helps the body work more efficiently by adjusting our diet with discipline.
- Blood Pressure: Intermittent fasting lowers blood pressure by improving gut health, reducing insulin levels, and decreasing oxidative stress and inflammation. This reduces the strain on the heart and blood vessels, further lowering blood pressure.
Different fasting methods, such as time-restricted eating, the 5:2 diet, and alternate-day fasting, offer various benefits for weight management and overall health. However, individual responses can vary, so it’s essential to consult with our healthcare professionals at Symbios to find the best approach for your needs.
Symbios Nutritional Care: Your Pathway to a Healthier Life
At Symbios, our goal is to provide you with a personalized and strategic plan to achieve a healthier lifestyle. Our team of nutritional experts is dedicated to long-term wellness, emphasizing nutrient-dense whole foods and sustainable lifestyle changes.
One key aspect of our health is reducing inflammation, which can cause many chronic diseases. Poor-quality foods can trigger an inflammatory response, leading to autoimmune disorders. By improving our diet and understanding the importance of nutrition, we can take proactive steps to combat inflammation and improve our overall well-being.
References
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- 10 Evidence-Based Health Benefits of Intermittent Fasting. (2016, August 16). Healthline.
- Buono, R., & Longo, V. D. (2019). When Fasting Gets Tough, the Tough Immune Cells Get Going—or Die. Cell, 178(5), 1038–1040.
- Cona, L. A. (2024, June 5). How Does Fasting Affect Stem Cells? (2024). Dvcstem.com.
- DONG, T. A., SANDESARA, P. B., DHINDSA, D. S., MEHTA, A., ARNESON, L. C., DOLLAR, A. L., TAUB, P. R., & SPERLING, L. S. (2020). Intermittent Fasting: A Heart Healthy Dietary Pattern? The American Journal of Medicine, 133(8).
- Elesawy, B. H., Raafat, B. M., Muqbali, A. A., Abbas, A. M., & Sakr, H. F. (2021). The Impact of Intermittent Fasting on Brain-Derived Neurotrophic Factor, Neurotrophin 3, and Rat Behavior in a Rat Model of Type 2 Diabetes Mellitus. Brain Sciences, 11(2).
- Hajek, P., Przulj, D., Pesola, F., McRobbie, H., Peerbux, S., Phillips-Waller, A., Bisal, N., & Myers Smith, K. (2021). A randomised controlled trial of the 5:2 diet. PloS One, 16(11), e0258853.
- Mihaylova, M. M., & Shaw, R. J. (2011). The AMPK signalling pathway coordinates cell growth, autophagy and metabolism. Nature Cell Biology, 13(9), 1016–1023.
- News in Health. (2019, November 22). To Fast or Not to Fast. NIH News in Health.
- Song, D.-K., & Kim, Y.-W. (2022). Beneficial effects of intermittent fasting: a narrative review. Journal of Yeungnam Medical Science, 40(1).
- The Beginner’s Guide to the 5:2 Diet. (2018, May 31). Healthline.
- Wang, Y., & Wu, R. (2022). The Effect of Fasting on Human Metabolism and Psychological Health. Disease Markers, 2022, 1–7.