Bio fillers have emerged as a cutting-edge, science-backed solution for individuals seeking natural facial rejuvenation and aesthetic enhancements without the use of synthetic materials. At Symbios, we leverage advanced bio filler techniques to deliver precise, personalized treatments that promote long-term skin health and restore lost facial volume.

By using autologous substances – materials harvested from your own body – bio fillers provide a safe and biologically compatible method of achieving youthful, natural-looking results. Here’s a closer look at the science behind bio fillers and their benefits in aesthetic medicine.

How Bio Fillers Work

Bio fillers are derived from autologous materials such as fat cells (autologous fat grafting) or platelet-rich plasma (PRP). Unlike traditional dermal fillers made from hyaluronic acid or other synthetic substances, bio fillers use the body’s own resources to restore lost volume, enhance contours, and improve skin texture. The primary types of bio fillers used in aesthetic practices include:

1. Autologous Fat Grafting: This procedure involves harvesting fat from a donor area of the patient’s body (such as the abdomen or thighs), processing it to purify the fat cells, and then re-injecting it into areas where volume loss or contouring is desired. Fat grafting is particularly useful for adding volume to the cheeks, under-eye hollows, lips, and nasolabial folds. Once re-integrated, the fat cells promote long-lasting volume enhancement while also improving skin quality due to the growth factors and stem cells present in the fat.
2. Platelet-Rich Plasma: PRP is a concentrated solution of platelets and growth factors obtained from your own blood. After centrifugation to separate the plasma from the red blood cells, the PRP is injected into areas that require rejuvenation. The high concentration of growth factors in PRP stimulates collagen production, tissue regeneration, and skin healing, making it an ideal option for improving fine lines, wrinkles, and overall skin texture.
3. Platelet Bio Filler: Platelet Bio Filler is an innovative, natural aesthetic treatment that uses the body’s own blood to rejuvenate and restore facial volume. The process begins with a small blood draw, similar to a routine blood test. The sample is then centrifuged to isolate the platelet-rich plasma, which is rich in growth factors that stimulate tissue regeneration. The PRP is gently warmed to create a gel-like consistency, enhancing its viscosity for smooth, precise application. Once injected into the treatment area, the platelet bio filler promotes collagen production and tissue repair, offering a natural, long-lasting solution for facial rejuvenation.

The Science Behind Bio Fillers

The effectiveness of bio fillers lies in the regenerative properties of the body’s own tissues. Fat tissue, in particular, contains a rich source of mesenchymal stem cells, which are multipotent cells capable of differentiating into various tissue types, including adipocytes (fat cells), osteocytes (bone cells), and chondrocytes (cartilage cells). When fat is transplanted into a new area, these stem cells contribute to tissue regeneration and repair, leading to improved skin elasticity, reduced wrinkles, and restored facial volume.

Similarly, platelet-rich plasma is packed with bioactive proteins and growth factors such as platelet-derived growth factor, transforming growth factor-beta, and vascular endothelial growth factor, all of which play crucial roles in wound healing, angiogenesis (formation of new blood vessels), and collagen synthesis. The localized release of these growth factors stimulates fibroblast activity in the skin, promoting collagen production and enhancing skin firmness over time.

Benefits of Bio Fillers

• Natural, Biocompatible Approach: One of the key advantages of bio fillers is their biocompatibility. Because the materials used – whether fat or PRP – are sourced from your own body, there is no risk of allergic reactions or immune responses. This makes bio fillers a particularly appealing option for patients with sensitivities to synthetic dermal fillers or concerns about foreign substances being introduced into their bodies.
• Long-Lasting Results and Tissue Regeneration: Unlike temporary hyaluronic acid fillers that degrade over time and require regular maintenance, bio fillers have the potential for longer-lasting and even permanent results. In the case of fat grafting, once the transplanted fat cells establish a blood supply and become integrated into the surrounding tissue, they can remain in place indefinitely. This makes fat grafting an ideal option for patients seeking lasting volumization without frequent touch-ups.
• Furthermore, the regenerative effects of PRP continue long after the initial treatment. By promoting collagen production and tissue repair, PRP injections offer progressive improvements in skin quality over several months, with results lasting up to a year or longer in some cases.
• Collagen Stimulation and Rejuvenation: Bio fillers go beyond merely adding volume to the face. The growth factors present in PRP and stem cells within fat tissue actively promote collagen synthesis and skin renewal, leading to improvements in skin texture, elasticity, and overall tone. This makes bio fillers particularly effective for treating fine lines, acne scars, and other skin imperfections that result from aging or environmental damage.
• Versatile Applications: At Symbios, we offer bio filler treatments for a variety of cosmetic concerns, including facial volume loss, contour enhancement, wrinkle reduction, and skin rejuvenation. Autologous fat grafting is ideal for restoring volume in the midface, smoothing deep wrinkles around the mouth and nose, and enhancing lip fullness. PRP, on the other hand, is highly effective for improving skin texture, treating dark under-eye circles, and addressing areas with fine lines or skin laxity. Because both fat and PRP are autologous, they can be safely combined with other aesthetic treatments, such as laser therapy or micro-needling, for even more dramatic results.

Ready to Get Started?

At Symbios, our Medical Spa specializes in bio filler treatments that combine the latest advances in regenerative medicine with a commitment to personalized patient care.  Dr. Stephen Luther is experienced in the most advanced fat grafting and PRP techniques to ensure that each treatment is tailored to your individual needs and goals. We conduct thorough consultations to assess your suitability for bio fillers and design a customized treatment plan to achieve the best possible results.

Whether you’re looking to restore lost facial volume, enhance your natural features, or rejuvenate your skin, bio fillers at Symbios offer a scientifically sound, natural solution to help you look and feel the best and most confident version of yourself.

References

1. Amiri, R., Khalili, M., Behzad Iranmanesh, Najmeh Ahramiyanpour, Mehran Karvar, & Mahin Aflatoonian. (2023). The innovative application of autologous biofillers in aesthetic dermatology. Italian Journal of Dermatology and Venereology, 158(4).
2. Borde Bisht, P., Gupta, S., & Kannan, C. (2020). Bio-filler: an effective facial rejuvenation tool – easy on pocket. Journal of Cutaneous and Aesthetic Surgery, 13(3), 243.